‘The FDA is a complete mess’: Trump makes fate of agency chief unclear as public trust plummits

Food and Drug Administration commissioner’s decisions have hurt staff morale and put his job in crosshairs

Donald Trump has signed off on a plan to fire Marty Makary, the commissioner of the US Food and Drug Administration (FDA), the Wall Street Journal https://www.wsj.com/health/healthcare/trump-planning-to-fire-fda-commissioner-marty-makary-34c072e2">reported on Friday, after a series of high-profile agency decisions put the FDA head in the crosshairs of the White House and Republican lawmakers.

Makary’s tenure at the FDA has been marked by several controversial decisions on drugs and vaccines amid plummeting staff morale over layoffs and the appointments of divisive officials.

Recent political clashes include abortion, drugs and vaping, but decisions to pull back publications on the safety of shingles and Covid vaccines, among other immunization decisions, have also rocked public health.

There have also been concerns about the transition from two clinical trials to one, the commissioner’s new priority review vouchers and “https://www.theguardian.com/us-news/2025/nov/24/menopause-hormone-therapy">data-free” regulatory decisions.