Marfan syndrome

Marfan syndrome Mileny ES Colovati 1 , Luciana RJ da Silva 1 , Sylvia S Takeno 1 , Tatiane I Mancini 1 , Ana R N Dutra 1 , Roberta S Guilherme 1 , Cláudia B de Mello 2 , Maria I Melaragno 1 and Ana B A Perez 1, CC BY 2.0

Genetic disorder of the connective tissue

Marfan syndrome (MFS) is a multi-systemic genetic disorder that affects the connective tissue. People with the condition are often tall and thin, with long arms, legs, fingers, and toes. They also typically have exceptionally flexible joints and abnormally curved spines. The most serious complications involve the heart and aorta, with an increased risk of mitral valve prolapse and aortic aneurysm. The lungs, eyes, bones, and the covering of the spinal cord are also commonly affected. The severity of the symptoms is variable.

Also known as...Marfan's syndrome and MFS
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